Due to its alkalinity, DCP wont work with some acidic active ingredients. in the urine, which can raise the risk of, Other Considerations for Calcium Phosphate, Dairy products, including milk, yogurt, and cheese, Dark green, leafy vegetables, like broccoli and kale, Calcium-fortified foods, like soy products, cereals, fruit juice, and milk alternatives, Lactose intolerance that limits your dairy intake, Consuming a lot of animal protein or sodium, both of which can cause calcium loss, Using corticosteroids as part of a long-term treatment plan, IBD or Celiac disease, which prevents your body from absorbing calcium properly, Have a history of kidney disease or stones, Antacids or any other calcium supplements, Doxycycline, minocycline, or tetracycline, Beef, chicken, and pork, especially meat from organs, Dairy, including milk, cheese, and yogurt. Aspartame,
Dicalcium phosphate is commonly added to breakfast cereals. Placing the phosphates in a layer . Copyright 2023 YOUR HEALTH REMEDY. It bonds with water molecules, drawing water out of food to keep it dry (x). Use this medication regularly to get the most benefit from it. Manufacturers use dicalcium phosphate in many products. Constipation and upset stomach may occur. Another hormone, calitonin, is likely involved in the reduction of bone resorption during periods of high plasma calcium. Pharmaceutical In the manufacture of pharmaceutical tablets and as a source of calcium and phosphorus in nutritional supplements. When calcium levels rise in your blood, phosphorous levels fall, and vice versa. The developed process achieves around 70% phosphorus recovery as an industrial-grade (19 wt% P) dicalcium phosphate dihydrate product with minimal iron, magnesium, and aluminum contamination, while also producing value-added calcium sulfate dihydrate (gypsum) and iron/magnesium byproducts. Dicalcium Phosphate E341(ii) is used as calcium supplement in Pharmaceutical,used as a tableting agent in some pharmaceutical preparations. For that reason, many people with mineral deficiencies take it to boost their calcium and phosphorus levels. Both salts are colourless solids. Few people experience problems from dicalcium phosphate. In addition to its use as buffers in drug formulation, Pure Di Calcium Phosphate Powder can be used as nutrient sources in nutraceuticals, pharmaceuticals and over the counter drugs. Dipotassium Phosphate Uses & Side Effects, http://www.sciencedirect.com/science/article/pii/037851739500077V, https://www.ncbi.nlm.nih.gov/pubmed/12115754, http://onlinelibrary.wiley.com/doi/10.1002/jbm.10257/abstract, Polygala Amarella (Dwarf Milkwort) Medicinal Uses. Dicalcium phosphate contains calciumessential for healthy bones, muscles, heart and bloodand phosphorusessential for healthy bones, teeth and cells (x)(x). Farmers often supplement their livestock feed with inorganic phosphorus. If you have any of the following health problems, consult your doctor or pharmacist before using this product: high calcium levels (hypercalcemia), kidney disease (including kidney stones), little or no stomach acid (achlorhydria), heart disease, disease of the pancreas, a certain lung disease (sarcoidosis), difficulty absorbing nutrition from food (malabsorption syndrome). GUARANTEED ANALYSIS: D Biotin,
Dibasic calcium phosphate is also found in some dietary calcium supplements (e.g. Therefore, if you are vegan, it is recommended to check with the producer to find out precisely the source of DCP. It is also used as a tableting agent in some pharmaceutical preparations, including some products meant to eliminate body odor. Acesulfame K,
Read more: Drugs and Treatment for Insomnia. 2000;16:521-55. Tricalcium phosphate is a supplement form of calcium phosphate used to treat or prevent calcium deficiency. Dicalcium Phosphate E341(ii) isused in Food,Beverage,Pharmaceutical,Health & Personal care products,Agriculture/Animal Feed/Poultry. This class of laxatives helps promote a bowel movement by drawing water into the bowel, which softens the stool and makes it easier to pass. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Hygienists use it to clean your teeth. However, there are several things you need to know before adding this supplement to your daily regimen. Dicalcium phosphate contains calciumessential for healthy bones, muscles, heart and bloodand phosphorusessential for healthy bones, teeth and cells (x)(x). 2008 Sep;53(3):268-73. doi: 10.1111/j.1834-7819.2008.00061.x. National Library of Medicines list ", Wellspan Health: calcium phosphate, tribasic (tricalcium phosphate).. As calcium supplement: in feed additive to enhance nutrition. Calcium phosphate dihydrate may increase the arrhythmogenic activities of Digoxin. Dibasic calcium phosphate is mainly used as a dietary supplement in prepared breakfast cereals, dog treats, enriched flour, and noodle products. Dicalcium Phosphate Dihydrate. The application such as in dog food, pet food, cat food, cattle feed and veterinary use. Sucralose,
Build, train, & validate predictive machine-learning models with structured datasets. Phosphorous can interfere with the human bodys use of other essential minerals, such as magnesium, iron, and zinc as well as it can cause diarrhea. Supplementing with dicalcium phosphate can help you strengthen your bones. If you believe you are experiencing an interaction, contact a healthcare provider immediately. Store at room temperature away from light and moisture. Vitamin D helps with the absorption of calcium. Properly discard this product when it is expired or no longer needed. 2H 2 O) is the most stable phase themodynamically when pH is 4.2 or lower ( Fig. A February 2015 article in Aquaculture Nutrition showed that young fish given dicalcium phosphate grew into larger, more muscular adults, and scientists have found similar results in many farm animals. US residents can call their local poison control center at 1-800-222-1222. Do not take other supplements/vitamins unless ordered by your doctor. Tell your doctor right away if you have any serious side effects, including: nausea/vomiting, loss of appetite, unusual weight loss, mental/mood changes, bone/muscle pain, headache, increased thirst/urination, weakness, unusual tiredness. Dicalcium Phosphate in Food Production Copyright@2006-2020 All rights reserved Foodchem International Corporation. document.getElementById( "ak_js_2" ).setAttribute( "value", ( new Date() ).getTime() ); Copyright @ 2020 Newseed Chemical Co., Limited. A significant correlation was found between the phosphorus extracted by 0.5N NaHCO 3 and the phosphorus uptake by the two crops from the various phosphates. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you have concerns that youre not getting enough calcium, your doctor can help. Contact Noah Chemicals today if you need a supply of calcium carbonate for near-term turnaround. Improve clinical decision support with information on. Calcium glucoheptonate can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Dicalcium phosphate can also replace fluoride as the best way to prevent tooth decay. However, too much dicalcium phosphate, or dicalcium phosphate taken in conjunction with other medications, can have negative consequences. Star 1 Generic Name Calcium phosphate dihydrate DrugBank Accession Number DB14481 Background Not Available Type Small Molecule Groups Approved Structure Download Similar Structures Weight Average: 172.086 Monoisotopic: 171.9449658 Chemical Formula CaH 5 O 6 P Synonyms Calcium monohydrogen phosphate dihydrate D.C.P. 2H 2 O) is the most stable phase themodynamically when pH is 4.2 or lower ( Fig. If you miss a dose, take it as soon as you remember. High calcium levels may indicate too much dietary calcium, too much supplemental vitamin D or bone disease (x). Many people using this medication do not have serious side effects. Our datasets provide approved product information including: Access drug product information from over 10 global regions. Calcium Phosphates are salts obtained from Phosphoric Acid. Calcium phosphate is on the FDA Generally Regarded as Safe List (GRAS). It also makes the kidneys excrete less calcium and activate vitamin D, which helps the body absorb more calcium. Tell your doctor if you are pregnant before using this medication. Dicalcium Phosphate E341 (ii) is used as food additive and supplement for calcium and phosphorous. If not stored according to recommendations, your supplements may change in consistency or potency. All rights reserved. Your body excretes the rest in the stool. More importantly, when the human body has very high levels of phosphorous, this mineral can join with calcium in the blood and form deposits in the muscles and other soft tissues, leading to calcification (hardening). Talk to your doctor if youre taking:. Kidney stones. InChI=1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2, Use our structured and evidence-based datasets to. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Your Health Remedy is a website for those who aspire to improve themselves and their life, as well as contribute to making the world a better place to live. High intake of milk, cheese, low-fat milk, ice cream, and total dairy and dietary calcium, may increase the risk of prostate cancer, according to a 2015 study done at the Faculty of Medicine, Trondheim, Norway. A January 2018 report in the Journal of Entomology and Zoology showed that dicalcium phosphate supplementation created high levels of circulating phosphorus. Calcium phosphates are salts derived from phosphoric acid.
They are used mainly as superphosphate fertilizers and are also popular leavening agents. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you develop kidney stones that are composed of calcium phosphate, you may need to adjust your diet. Synthetic bone also allows drug delivery to the healing area via nanoparticles. Its made up of charged particles of phosphate and calcium. [4] Various calcium phosphate minerals are used in the production of phosphoric acid and fertilizers. As calcium supplement: in tablets to provide calcium. European Pharmacopoeia (EP 3rd ed.) Calcium Phosphate, Dibasic 825 Mg Calcium/2.8 Gram Oral Powder, Enter your medication into the WebMD interaction checker, Treating Opioid Use Disorder With Medications, prevention of a low amount of calcium in the blood, FDA Labeling for calcium phosphate on RxList. Dont take this supplement if youre pregnant or nursing, and take only the recommended amount to prevent the following adverse side effects: red, itchy, irritated skin from continual skin contact; loss of appetite, nausea or vomiting; other gastrointestinal problems and frequent urination. Dicalcium phosphate is used as a food additive, it is found in some toothpastes as a polishing agent and is a biomaterial. Calcium phosphate reacts with acid in the stomach to raise the pH 3. At 60C the anhydrous form is precipitated:[3], To prevent degradation that would form hydroxyapatite, sodium pyrophosphate or trimagnesium phosphate octahydrate are added when for example, dibasic calcium phosphate dihydrate is to be used as a polishing agent in toothpaste.[1]. Other calcium phosphates are termed dibasic, meaning they have two replaceable hydrogen atoms. The inorganic phosphorus deriving from food additives is mainly absorbed in the amount of approximately 80-90% as free orthophosphate. If you think you may have a serious medical problem, get medical help right away. As nutritional supplement: in biscuit, breakfast cereals, and infant formula to enhance nutrition. Dicalcium Phosphate E341(ii) isused as food additive and supplement for calcium and phosphorous. Keep all medical and lab appointments. This is essential information since approximately 15 percent of all men will be diagnosed with prostate cancer during their lifetime. A review of the marketed tablets and capsules indicated that several of them contain calcium phosphate. Calcium can decrease the absorption of other drugs such as bisphosphonates (for example, alendronate), tetracycline antibiotics (such as doxycycline, minocycline), estramustine, levothyroxine, and quinolone antibiotics (such as ciprofloxacin, levofloxacin). 4 Potential Benefits of Silica Supplements, American Association of Pharmaceutical Scientists, What You Really Need to Know About Supplements, Acta Biomaterialia: Review of Potential Health Risks Associated With Nanoscopic Calcium Phosphate, EFORT Open Reviews: Bioceramics and Bone Healing, Open Dentistry Journal: Overview of Calcium Phosphates Used in Biomimetic Oral Care, Journal of Entomology and Zoology Studies: Relative Bioavailability of Phosphorus From Different Inorganic Sources in Rats, Aquaculture Nutrition: Comparison of the Effect of Dietary Fungal Phytase and Dicalcium Phosphate Supplementation on Growth Performances, Feed and Phosphorus Utilization of Tra Catfish Juveniles, PJMHS: Effect of Calcium Supplementation in Postmenopausal Women and Changes in Serum Calcium and Phosphorus Level, American Association of Pharmaceutical Scientists: Surface Acidity and Solid-State Compatibility of Excipients With an Acid-Sensitive API, Bulletin of Pharmaceutical Research: Pharmaceutical Diluents and Their Unwanted Effects. If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. More research interest in DCP has emerged because DCP may be a better alternative to bone grafts, which carry risks such as tissue rejection and transmittable disease (x). This document does not contain all possible drug interactions. The reduction in PTH secretion also reduces the amount of vitamin D metabolized to its active form, calcidiol. A February 2016 report in the Bulletin of Pharmaceutical Research noted that the chemical can be a skin irritant. Selected from data included with permission and copyrighted by First Databank, Inc. It is on FDAs GRAS (Generally Recognized as Safe) exemption list, plus, it is broadly accepted and used as a safe food additive and supplement in many countries. Dicalcium phosphate supplements are available as pills, capsules and in complexes for bone support. Hypertension affects more than 80 million people in the United States and usually has no signs and symptoms. Calcium decreases the effectiveness of the anti-epileptic drug phenytoin, and the antibiotics quinolone and tetracycline by decreasing absorption of the drugs. Since calcidiol increases the expression of calcium dependent ATPases and transient receptor potential cation channel subfamily V member 6 (TRPV6) both of which are involved in calcium uptake from the gut, a reduction in calcidiol results in less calcium absorption. Phosphorus is an essential macro-mineral and it is one of the most abundant minerals in the body. Calcium phosphate is most often used to treat calcium deficiencies in your diet. Dicalcium Phosphate is widely used as pH regulator in Cosmetics. People with an allergy to dicalcium phosphate could develop contact dermatitis, a specific allergic reaction characterized by redness, swelling or itching on skin areas that come into direct contact with an irritating substance. Calcium chloride can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy. . Dicalcium Phosphate is a white, tasteless, microcrystalline powder that is frequently utilized in foods and beverages as a buffering agent, a dough modifier, an emulsifier, a leavening agent, a nutritional supplement, or a stabilizer. [3] In milk, it exists in a colloidal form in micelles bound to casein protein with magnesium, zinc, and citratecollectively referred to as colloidal calcium phosphate (CCP). Dicalcium Phosphate (DCP), also referred to as E341, is a white, odorless powder, with the chemical formula - CaHPO4. Let's break down the health benefits of each mineral: Benefits of Calcium Your body needs calciumevery day. This is not a complete list of possible side effects. If any of these effects last or get worse, tell your doctor or pharmacist promptly. An example of the overall setting reaction in the formation of "-TCP/MCPM" (-tricalcium phosphate/monocalcium phosphate) calcium phosphate cements is:[5]. According to evidence gathered by the National Library of Medication, National Institutes of Health, while calcium supplementation is often well-tolerated, high levels could upset the gastrointestinal system. Over time, this depletion can lead to bone disease like osteoporosis (x). Potassium phosphate- for use only in agricultural products labeled "made with organic (specific ingredients or food group(s)," prohibited in agricultural products labeled "organic". If you take the supplement on an empty stomach, there may not be enough stomach acid for proper absorption. According to both the evidence gathered by the National Library of Medication, National Institutes of Health, and Pharmacy Health, ingestion of dicalcium phosphate could increase the severity of symptoms in people who are already experiencing problems with diarrhea, parathyroid disease, lung disease, kidney stones or other stomach-related problems. Dicalcium phosphate supplementation creates high levels of circulating phosphorus. Good compression characteristics can be obtained with 10-33% dicalcium phosphate and 66-90% microcrystalline cellulose with 0.5% magnesium stearate and as little as 0.1% sodium starch glycolate. Your bones store most of your bodys phosphorus, which is responsible for healthy nerve and muscle functions (x)(x). When to supplement your calcium intake. It may also be used in certain patients to make sure they are getting enough calcium (such as women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).Calcium plays a very important role in the body. It is also used as an anti-caking agent in powdered food items and as an additive in some processed foods to boost calcium content. Dicalcium Phosphate E341(ii) is used as texture stabilizer in various other industries. You must consume calcium regularly, or your body will begin to move too much of it from your bones into your blood stream. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Annu Rev Physiol. Calcium is an important mineral found naturally in food. Aust Dent J. You can use both as over-the-counter calcium and phosphorus supplements. It's made up of charged particles of phosphate and calcium. The availability of dicalcium phosphate in powder and granulated form mixed with ammonium sulfate, was tested in a greenhouse experiment. A recent validation study shows that together, the acid process after degreasing anddemineralisation has a total clearance of infectivity of 2.6 log10. Image Credit: Science Photo Library/Science Photo Library/GettyImages Manufacturers use dicalcium phosphate in many products. Does Calcium Phosphate, Dibasic 825 Mg Calcium/2.8 Gram Oral Powder interact with other drugs you are taking? See how this product scores for common concerns. Dicalcium Phosphate E341(ii) uses as follows: Dicalcium Phosphate E341(i) is used as nutritional supplement and buffering agent in food such asin biscuits, milk powder, drinks, ice cream,biscuit, breakfast cereals, infant formula,in noodles and baked food. Vitamin D is also made by the body as a result of exposure to the sun. 2013;75:535-50. doi: 10.1146/annurev-physiol-030212-183748. The substance is used, among other things, as a dietary supplement, antacid or for the treatment of calcium deficiency. Moreover, men who took more than 2,000 mg of calcium per day (from supplements) had a 400 percent higher risk of getting prostate cancer than men taking less than 500 mg per day, according to a 1998 study issued in Cancer Research medical journal. If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Dicalcium Phosphate (DCP) is often used as a leavening agent, dough modifier, buffer, nutritional supplement, emulsifier, and stabilizer in flour, cake, pastry, and baked goods. Dicalcium phosphate makes health products like toothpaste effective and safe. swelling of the face, lips, tongue, or throat. Symptoms of overdose may include: nausea/vomiting, loss of appetite, mental/mood changes, headache, weakness, tiredness. According to the Material Safety Data Sheet for powdered dicalcium phosphate, inhalation of the dust of dicalcium phosphate powders may irritate the lungs and nasal passages, causing coughing and sneezing. In toothpaste it provides a source of calcium and phosphate ions to support remineralization of the teeth . In a continuous process CaCl2 can be treated with (NH4)2HPO4 to form the dihydrate: A slurry of the dihydrate is then heated to around 6570C to form anhydrous CaHPO4 as a crystalline precipitate, typically as flat diamondoid crystals, which are suitable for further processing. Annu Rev Cell Dev Biol. They look like a white powder and have no smell (x). Store properly. Dicalcium phosphate is a calcium supplement commonly found in prepared breakfast cereals, in pharmaceuticals as an inert ingredient to bind tablets, and in toothpastes. generally isnt true, as long as the calcium is being taken with food. This application file is based on limited review of Foodchem International Corporation. Xylitol,
In the United States, prostate cancer is the 2nd leading cause of cancer death in adult males. Drink water. As you age, bone mineral density also declines, which can put you at increased risk of fracture. Two hormones control calcium levels in the blood: parathyroid hormone and calcitonin. Yet it doesn't combine well with acidic drugs like the sleeping pill temazepam. Pharmaceutical companies often use DCP to make tablets, especially since its insoluble and ideal for use in time-release pills (x). It is also known as dibasic calcium phosphate or calcium monohydrogen phosphate. Dicalcium Phosphate (DCP) is often used as a leavening agent, dough modifier, buffer, nutritional supplement, emulsifier, and stabilizer in flour, cake, pastry, and baked goods. Treating Constipation Sodium phosphate is found in over-the-counter enemas and other oral medications and is effective in the treatment of constipation. Over time, it will dry out and break down skin cells. Dicalcium Phosphate is the sodium salt that is derived from phosphate rock through a simple chemical reaction between sodium hydroxide (NaOH) and phosphoric acid (H3PO4) Dicalcium Phosphate is an industrial chemical with multiple uses. It doesnt dissolve completely in water, so you can blend it into juices or smoothies or put in capsules. Aluminum hydroxide can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Natamycin,
Dicalcium Phosphate (DCP), also referred to as E341, is a white, odorless powder, with the chemical formula CaHPO4. Aside from its use as a dietary supplement, the anhydrous (dry) DCP works as an anti caking agent for food. Manufacturers often add it to teeth whiteners as an abrasive to gently polish your teeth. Surgeons sometimes use DCP during synthetic bone grafts because its so similar to natural bone. The reduction in calcium flux increases the amount of calcium deposited in bone resulting in an increase in bone mineral density. It is also used in some toothpastes as a tartar control agent.[8]. However, there are several things you need to know before adding this supplement to your daily regimen.. McGraw Hill. Check the labels on all your prescription and nonprescription/herbal products (such as antacids, vitamins) because they may contain calcium. As a nutritional supplement, Dicalcium Phosphate can be used in a wide variety of industries including: food production, pharmaceutical, cosmetics, agriculture/animal feed, and various other industries. Similar to calcium, vitamin D helps the body absorb phosphate. Also, there is no limit on the dosage of intake. Its also very important for healthy digestion. It may be used to treat conditions caused by low calcium levels such as bone loss ( osteoporosis ), weak bones ( osteomalacia / rickets ), decreased activity of the parathyroid gland (. This is because your stomach produces acid to break down food. Calcium is renowned for its important role in bone health. If it is near the time of the next dose, skip the missed dose. Dicalcium phosphate makes health products like toothpaste effective and safe. In addition,it is found in some types oftoothpaste as well as a calcium supplement in some pharmaceutical preparations. Calcium gluconate can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Before taking calcium, tell your doctor or pharmacist if you have any allergies. In the US - Call your doctor for medical advice about side effects. 1 ). Parathyroid hormone tells the bones when they need to release calcium into the blood. Calcium phosphate is a widely used pharmaceutical excipient as binder and filler in solid oral dosage forms which include compressed tablets and hard gelatin capsules. In fact, calcium actually aids in your bodys ability to block potentially harmful substances from entering your digestive tract and causing kidney stones., Too much sodium can lead to more calciumin the urine, which can raise the risk of kidney stones. [, Barrett KE, Barman SM, Boitano S, Brooks HL (2012). Read more: Best Supplements for Bone Healing. It will need to be alongside other excipients. This can create kidney stones, weaken the bones, and interfere with how the brain and heart work (like dangerously low blood pressure and an irregular heartbeat). Calcium does this by stimulating a G-protein coupled calcium receptor on the surface of parathyroid cells. Read more: What You Really Need to Know About Supplements. Dicalcium Phosphate, Anhydrous is a white, odorless, tasteless powder. Dicalcium phosphate has wide applications to stimulate growth in ruminants and other farm animals. Damaged bone doesnt always regenerate on its own and may require grafts for repair. Molecular Weight 136.06 g/mol Computed by PubChem 2.1 (PubChem release 2021.05.07) Component Compounds CID 1004 (Phosphoric Acid) CID 3681305 (Hydrogen phosphate) CID 5460341 (Calcium) Dates Create: 2005-03-27 Modify: 2023-07-01 Description Calcium hydrogenphosphate is a calcium phosphate. Certificates of Analysis are available on request. Therefore, mixture of calcium phosphate powder which supply Ca 2+ and ions and the pH of the paste is 4.2 or lower could be the brushite cement. As Friction agent: in toothpastes to improve cleaning efficiency. DCP binding properties are only moderate. From birth to mating, milking and production, every stage of their life demands essential nutritional value that they must consume to stimulate growth. This technique compensates for the low availability and poor digestibility of food-related phosphorus. People experiencing any one of these symptoms should first consult a physician before taking dicalcium phosphate supplements. It helps your body form bones and teeth, cell membranes and DNA. Many foods naturally contain healthy amounts of calcium and phosphorus; dairy, leafy vegetables, almonds, sardines and figs are all rich in calcium. Interestingly, these effects can spread to areas which haven't seen direct contact. H 2 O. USES Dentifrice As a polishing agent. [, UniProt: Calcium and integrin-binding protein 1 [, Uniprot: Programmed cell death protein 6 [, UniProt: Calcineurin B homologous protein 1 [, UniProt: Translationally-controlled tumor protein [, UniProt: Calcium and integrin-binding family member 2 [, UniProt: Calcium-dependent secretion activator 1 [, UniProt: Calcium-dependent secretion activator 2 [, Biber J, Hernando N, Forster I: Phosphate transporters and their function.